Key Features:
- Suitable for separating polar compounds under extremely low to moderate pH conditions
- No endcapping, eliminating the problem of endcapping agents hydrolyzing under acidic conditions and altering C18 selectivity
- The stable and hydrolysis-resistant surface bonding extends column life
- Excellent separation of polar analytes under acidic conditions
- Made from ultrapure spherical silica, resulting in sharp peak shapes and excellent reproducibility
Technical Specifications:
| Model | AY-G-C18-LP |
| Bonding phase | Octadecyl group |
| Particle size (um) | 3,3.5,4,5,10 | 3,3.5,5 |
| Aperture (A) | 120 | 300 |
| Specific surface area (m2/g) | 320 | 90 |
| Carbon load (%) | 10 | 5 |
| End capped tail | YES |
| pH range | 0.5-8.0 |
| USP classification | L1 |
Applications:
- Drug Discovery – Separation of basic drugs, peptides, and polar APIs using acidic mobile phases
- Bioanalysis – Detection of acidic metabolites, nucleotides, and hydrophilic drugs
- Traditional Chinese Medicine (TCM) – Improved retention of acid-stable polar compounds
- Food Testing – Separation of acidic preservatives and water-soluble additives
- Environmental Analysis – Identification of acid-stable polar contaminants
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