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AYB-C18 is a universal liquid chromatography column suitable for multi-component sample analysis, with excellent reproducibility and flexible method development under a range of complex chromatographic conditions.

AY-B-C18 HPLC Column

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Product Detail

Product Features:

1. Can directly replace international mainstream brand C18 columns, significantly reducing costs

  • Perfectly matching the key parameters of classic models such as Agilent ZORBAX Eclipse Plus C18, Waters Symmetry C18, Phenomenex Luna C18 (2) (5 μ m, 100 Å, 14% carbon loading, double capped).
  • Consistent performance in pharmacopoeia (USP/ChP), EPA, GB and other standard methods, saving 30-50% of procurement costs and reducing supply chain dependence.

2. High reproducibility and batch stability ensure the reliability of QC data

  • Adopting strictly controlled bonding process and silicone matrix to ensure retention time RSD<0.5%, meeting the stringent requirements of GMP/GLP laboratory for data integrity.
  • The performance between batches is highly consistent, avoiding frequent method revalidation.

3. Universal USP L1 certification, widely compatible with standard analytical methods

  • Compliant with USP L1 classification (octadecylsilane bonded silica gel), it can be directly used for:
  • Drug related substances and content determination (such as antibiotics, vitamins)
  • Detection of pesticide residues and additives in food
  • Analysis of Polycyclic Aromatic Hydrocarbons (PAHs) and Phenols in Environmental Samples

4. Optimize packing design to balance separation efficiency and durability

  • 300 m ²/g high specific surface area+14% carbon loading: provides strong retention capacity, suitable for complex multi-component separation;
  • Double sealing technology: effectively shields residual silicon hydroxyl groups, reduces tailing of alkaline compounds, and enhances peak symmetry;
  • PH 2.0-8.0 stable working range: covering the vast majority of reverse phase chromatography application scenarios.

5. Flexible support for dual requirements of method development and daily detection

  • It exhibits robustness under gradient elution, isometry analysis, and different mobile phase systems (methanol/acetonitrile);
  • Suitable for HPLC and UHPLC (depressurization mode) platforms, it is an ideal bridge column for research and development to production.


Product Parameters:

ModelAY-B-C18
Bonding phaseParticle size (um)Aperture (A)Octadecyl group
Specific surface area (m2/g)5
Carbon load(%End capped tail100
Specific surface area (m2/g)300
Carbon load(%)14
End capped tailYES
PH range2.0-8.0
USP classifcationL1


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Product Detail

Product Features:

1. Can directly replace international mainstream brand C18 columns, significantly reducing costs

  • Perfectly matching the key parameters of classic models such as Agilent ZORBAX Eclipse Plus C18, Waters Symmetry C18, Phenomenex Luna C18 (2) (5 μ m, 100 Å, 14% carbon loading, double capped).
  • Consistent performance in pharmacopoeia (USP/ChP), EPA, GB and other standard methods, saving 30-50% of procurement costs and reducing supply chain dependence.

2. High reproducibility and batch stability ensure the reliability of QC data

  • Adopting strictly controlled bonding process and silicone matrix to ensure retention time RSD<0.5%, meeting the stringent requirements of GMP/GLP laboratory for data integrity.
  • The performance between batches is highly consistent, avoiding frequent method revalidation.

3. Universal USP L1 certification, widely compatible with standard analytical methods

  • Compliant with USP L1 classification (octadecylsilane bonded silica gel), it can be directly used for:
  • Drug related substances and content determination (such as antibiotics, vitamins)
  • Detection of pesticide residues and additives in food
  • Analysis of Polycyclic Aromatic Hydrocarbons (PAHs) and Phenols in Environmental Samples

4. Optimize packing design to balance separation efficiency and durability

  • 300 m ²/g high specific surface area+14% carbon loading: provides strong retention capacity, suitable for complex multi-component separation;
  • Double sealing technology: effectively shields residual silicon hydroxyl groups, reduces tailing of alkaline compounds, and enhances peak symmetry;
  • PH 2.0-8.0 stable working range: covering the vast majority of reverse phase chromatography application scenarios.

5. Flexible support for dual requirements of method development and daily detection

  • It exhibits robustness under gradient elution, isometry analysis, and different mobile phase systems (methanol/acetonitrile);
  • Suitable for HPLC and UHPLC (depressurization mode) platforms, it is an ideal bridge column for research and development to production.


Product Parameters:

ModelAY-B-C18
Bonding phaseParticle size (um)Aperture (A)Octadecyl group
Specific surface area (m2/g)5
Carbon load(%End capped tail100
Specific surface area (m2/g)300
Carbon load(%)14
End capped tailYES
PH range2.0-8.0
USP classifcationL1


AY-B-C18 HPLC Column
AYB-C18 is a universal liquid chromatography column suitable for multi-component sample analysis, with excellent reproducibility and flexible method development under a range of complex chromatographic conditions.
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