Product Features:
1. Can directly replace international mainstream brand C18 columns, significantly reducing costs
- Perfectly matching the key parameters of classic models such as Agilent ZORBAX Eclipse Plus C18, Waters Symmetry C18, Phenomenex Luna C18 (2) (5 μ m, 100 Å, 14% carbon loading, double capped).
- Consistent performance in pharmacopoeia (USP/ChP), EPA, GB and other standard methods, saving 30-50% of procurement costs and reducing supply chain dependence.
2. High reproducibility and batch stability ensure the reliability of QC data
- Adopting strictly controlled bonding process and silicone matrix to ensure retention time RSD<0.5%, meeting the stringent requirements of GMP/GLP laboratory for data integrity.
- The performance between batches is highly consistent, avoiding frequent method revalidation.
3. Universal USP L1 certification, widely compatible with standard analytical methods
- Compliant with USP L1 classification (octadecylsilane bonded silica gel), it can be directly used for:
- Drug related substances and content determination (such as antibiotics, vitamins)
- Detection of pesticide residues and additives in food
- Analysis of Polycyclic Aromatic Hydrocarbons (PAHs) and Phenols in Environmental Samples
4. Optimize packing design to balance separation efficiency and durability
- 300 m ²/g high specific surface area+14% carbon loading: provides strong retention capacity, suitable for complex multi-component separation;
- Double sealing technology: effectively shields residual silicon hydroxyl groups, reduces tailing of alkaline compounds, and enhances peak symmetry;
- PH 2.0-8.0 stable working range: covering the vast majority of reverse phase chromatography application scenarios.
5. Flexible support for dual requirements of method development and daily detection
- It exhibits robustness under gradient elution, isometry analysis, and different mobile phase systems (methanol/acetonitrile);
- Suitable for HPLC and UHPLC (depressurization mode) platforms, it is an ideal bridge column for research and development to production.
Product Parameters:
| Model | AY-B-C18 |
| Bonding phaseParticle size (um)Aperture (A) | Octadecyl group |
| Specific surface area (m2/g) | 5 |
| Carbon load(%End capped tail | 100 |
| Specific surface area (m2/g) | 300 |
| Carbon load(%) | 14 |
| End capped tail | YES |
| PH range | 2.0-8.0 |
| USP classifcation | L1 |