Key Features:
1. Advanced Coating Technology
Polysaccharide Selector: Utilizes a specific amylose derivative as the chiral selector, offering unique stereoselectivity compared to cellulose-based phases.
Physical Coating: The chiral agent is physically coated onto the silica surface, preserving the natural conformation of the selector for high recognition ability.
2. Excellent Solvent Tolerance
Engineered for robustness, the Amy-D phase demonstrates superior solvent tolerance compared to traditional coated columns, ensuring a longer column lifespan and stable performance.
3. Versatile Chromatographic Mode Compatibility
Multi-Mode Application: Compatible with Normal Phase (NP), Reversed Phase (RP), and Polar Organic (PO) modes. This flexibility allows users to optimize separation conditions without changing columns.
4. High Sample Loading Capacity
Designed for both analytical and preparative applications, the column offers high loading capacity, making it suitable for the scale-up from analysis to semi-preparative purification.
Technical Specifications:
| Model | AY-G-HIL-30 |
| Bonded phase | Polyacrylamide group |
| Particle size (μm) | 3,5 |
| Pore size (Å) | 120 |
| Specific surface area (m²/g) | 320 |
| Carbon load (%) | 7 |
| Endcapping | no |
| pH range | 2.0~8.0 |
| USP classification | / |
Application:
Pharmaceutical Analysis: Chiral purity testing and method development for active pharmaceutical ingredients (APIs).
Preparative Separation: Purification of enantiomers due to high loading capacity.
Chemical Research: Analysis of chiral compounds where versatile solvent compatibility is required.